New Research and Novel Scientific Discoveries


New Diagnostic Criteria/Cut-offs/prediction equations for Indians

  • New potential non-invasive test for measuring hepatic metabolism and for prediction of hyperglycemia in Indians (First Study in World)
  • New diagnostic cut-off for diagnosis of obesity (BMI) for Indians.
  • New diagnostic cut-off for diagnosis of abdominal obesity (waist circumference) for Indians.
  • New cut-offs for body mass index, waist circumference, and lipid parameters for Indian adolescents (First Study on Asians)
  • New definition for diagnosis of Syndrome X for Indian adults(First Study in Asians).
  • New definition for diagnosis of Syndrome X for Indian adolescents (First Study in Asians).
  • New diagnostic criteria and classification of rare fat disorders (Acquired Generalized and Acquired Partial Lipodystrophies) (First Study in World).
  • New prediction criteria for childhood type 2 diabetes in Indians (First Study in Asians).
  • New cut-offs for total abdominal fat, intra-abdominal fat and subcutaneous fat for Asian Indians (First Study in World).
  • Predictive equations for abdominal fat depots for Indian (First Study in Asians)
  • New limit for saturated fat intake for Asian Indian children (First Study in World).
  • New phenotypic predictors for diabetes and the metabolic syndrome ('buffalo hump' and 'double chin') (First Study in World)
  • Dietary predictor (n-6 fatty acid) for insulin resistance in Asian Indian adolescents (First Study in World)
  • New prediction equation for fatty liver (First Study in World)
  • New cut-offs for insulin levels for diagnosis of insulin resistance in Asian Indian adolescents (First Study in World)
  • New and correct methodology for measurement of waist circumference (Second Study in the world)

New Findings in Indian Population

  • High prevalence of abdominal obesity in Indian population.
  • High prevalence of obesity in adolescent children.
  • High prevalence of diabetes, dyslipidemia, and heart disease in the urban poor population (First Study in World).
  • High prevalence of risk factors for heart disease in children (First Study in Asians).
  • Characteristics of body fat distribution in Indians. (Second Study in Indians).
  • Importance of subcutaneous fat as predictor of insulin resistance and diabetes (First Study in Asians)
  • Imbalanced dietary profile of poor people in urban slums, schoolchildren, and women (First Study in World).
  • Abnormality of gene Apolipoprotein E in young patients developing heart attack.
  • Abnormalities of gene APOC3 in promoting Syndrome X in Indians.
  • High prevalence of CRP in urban population including those residing in urban slums (First Study in World).
  • Significance of high CRP levels vis-à-vis cardiovascular risk factors in Indians.
  • High lipids in muscles of Asian Indians (First Study in Asians)
  • Importance of omega-6 fatty acids in pathophysiology of syndrome x in Indian children.
  • Fatty liver as a predictor of insulin resistance.
  • New genetic correlate of obstructive sleep apnea (TNF-alpha, PPAR (Pro12Ala) and Neuropeptide-Y (Leu7Pro) gene polymorphisms) (First Study in Asians)

New Laboratory Test for Diabetes

  • A new test for diabetes (Hb-AGE) developed with Indian Institute of Technology, Delhi (First Study in World).
  • Development of a new method for measurement of Hb-AGE, the new blood sugar monitoring protein

Novel Use of Drug in Diabetes

  • Use of Simvastatin in the prevention and treatment of diabetic retinopathy (First study in World).

Artificial Neural Network Analysis

  • Using this novel statistical method, we have identified predictors of hyperglycemia in order of importance. (First Study in Asians)

New findings of brain dysfunction in young patients with diabetes and hypertension.

  • First Study in World

Decrease in cerebral blood flow in patients with dyslipidemia.

  • First Study in Asians

Importance of weight resistance training for improvement of diabetes.

  • First Study in Asians

High homocysteine level as an important cardiac risk factor in Indians residing in urban slums.